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Built in 2000 alongside the Grand Hotel Duca d'Este, this 44-room hotel looks onto a tropical garden that unites and integrates the two buildings. Fully air-conditioned, the hotel features a lobby with 24-hour reception and check-out service, hotel safe and lift access. There is an on-site restaurant, room and laundry services are provided, and guests arriving by car can leave their vehicles in the hotel's own private car park. Guests can make use of all the amenities offered by the Grand Hotel Duca d'Este, and younger guests can enjoy the children's playground.

All of the guest rooms are pleasantly furnished, welcoming guests with all the modern comforts. The rooms are en suite and include hairdryer, direct dial telephone, TV set, minibar and a safe. Double beds and air conditioning/heating units come in all accommodation as standard.

A breakfast is served daily in buffet style, and midday and evening meals can be ordered à la carte or from a set menu.

The hotel grounds include an indoor heated pool, as well as an outdoor pool. Facilities include a wellness center with gym, sauna, Turkish bath and indoor pool. Terme Di Roma has been designed in Belle Époque style. It features thermal baths with 4 sulphurous water swimming pools in an area covering over 5,000 m². Guests wishing to play golf can head to the Marco Simone Golf Club, just 5 km from the hotel.

From Rome Leonardo da Vinci Fiumicino Airport: Take the train to Rome, alighting at Tiburtina or Termini railway station. From the railway station (Tiburtina or Termini), take underground line B as far as Ponte Mammolo station. From here, take the line bus heading to Tivoli Via Tiburtina (the bus leaves every 10 to 15 minutes). The line bus stop is just in front of the hotel. From Tiburtina station there is a train for Tivoli Terme station, leaving approximately every hour. Tivoli railway station is situated 500 m from the hotel.